Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | DGKA | P23743 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127343 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL21983887 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL8662579 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL10457574 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL21983635 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL20500825 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL9615678 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL11325730 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL20869798 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 | |
| SCHEMBL8662076 | 1.00 | TSHR (0.65) | TSHRDGKAALDH1A1LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405873-A1 | Long chain diol diesters as low calorie fat mimetics | NABISCO, INC. (US) | 1991-01-02 | — | — | EP | disclosed |