Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853348 | 0.91 | GBA1 (0.35) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL10436376 | 0.87 | MEN1 (0.38) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL9853323 | 0.81 | KMT2A (0.38) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL9815008 | 0.80 | GBA2 (0.60) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL10436366 | 0.79 | CNR1 (0.34) | GBA1UGCGGBA2TSHRTDP1 | |
| SCHEMBL2560886 | 0.74 | KMT2A (0.64) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL8979416 | 0.74 | KMT2A (0.64) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL9815036 | 0.74 | KMT2A (0.64) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL10770344 | 0.74 | KMT2A (0.64) | GBA1UGCGGBA2KMT2AMEN1 | |
| SCHEMBL15511217 | 0.74 | KMT2A (0.64) | GBA1UGCGGBA2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417535-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-20 | — | — | EP | claimed |
| EP-0417535-A2 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-20 | — | — | EP | disclosed |