Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449866 | 0.88 | LRRK2 (0.57) | LRRK2IDO1KMT2AALDH1A1AGTR1 | |
| SCHEMBL458707 | 0.86 | LRRK2 (0.51) | LRRK2IDO1KMT2AALDH1A1TDP1 | |
| SCHEMBL10085220 | 0.86 | LRRK2 (0.51) | LRRK2IDO1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL17560972 | 0.86 | LRRK2 (0.55) | LRRK2IDO1KMT2AALDH1A1AGTR1 | |
| SCHEMBL30455414 | 0.86 | LRRK2 (0.51) | LRRK2IDO1KMT2AALDH1A1TDP1 | |
| SCHEMBL10084821 | 0.85 | KMT2A (0.58) | LRRK2IDO1KMT2AALDH1A1TDP1 | |
| SCHEMBL98437 | 0.85 | KMT2A (0.58) | LRRK2IDO1KMT2AALDH1A1TDP1 | |
| SCHEMBL19586520 | 0.84 | KMT2A (0.57) | LRRK2IDO1KMT2AALDH1A1TDP1 | |
| SCHEMBL19449855 | 0.82 | LRRK2 (0.50) | LRRK2IDO1KMT2AAGTR1POLB | |
| SCHEMBL5820588 | 0.80 | LRRK2 (0.51) | LRRK2IDO1KMT2AALDH1A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | disclosed |