Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868747 | 0.86 | KDM4E (0.46) | MAPTTSHRP2RX3GRM5OPRM1 | |
| SCHEMBL7608437 | 0.84 | MAPT (0.67) | MAPTP2RX3L3MBTL1GAACYP1A2 | |
| SCHEMBL17456362 | 0.83 | MAPT (0.59) | MAPTP2RX3L3MBTL1GAACYP1A2 | |
| SCHEMBL22453223 | 0.82 | MAPT (0.57) | MAPTLMNATSHRNPSR1P2RX3 | |
| SCHEMBL27111298 | 0.78 | MAPT (0.54) | MAPTP2RX3L3MBTL1GAACYP1A2 | |
| SCHEMBL7612234 | 0.78 | MAPT (0.56) | MAPTLMNAP2RX3L3MBTL1GAA | |
| SCHEMBL8780569 | 0.77 | MAPT (0.70) | MAPTL3MBTL1GAACYP1A2RECQL | |
| SCHEMBL7613351 | 0.76 | MAPT (0.61) | MAPTP2RX3L3MBTL1GAACYP1A2 | |
| SCHEMBL875715 | 0.75 | MAPT (0.55) | MAPTTSHRL3MBTL1GAACYP1A2 | |
| SCHEMBL31264286 | 0.75 | MAPT (0.55) | MAPTTSHRL3MBTL1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015476-A1 | SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES | DOWELANCO (US) | 1991-10-17 | — | — | WO | disclosed |
| EP-0450712-A2 | Substituted cyclohexanediones and their herbicidal uses | DOWELANCO (US) | 1991-10-09 | — | — | EP | disclosed |
| US-5013352-A | Grassy weeds in presence of crops | DOWELANCO (US) | 1991-05-07 | — | — | US | disclosed |