Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725453 | 0.76 | KDM4E (0.38) | PIM1PIM3 | |
| SCHEMBL10677636 | 0.76 | DYRK1A (0.32) | — | |
| SCHEMBL9533974 | 0.68 | — | — | |
| SCHEMBL31749048 | 0.66 | — | — | |
| SCHEMBL11204869 | 0.65 | — | — | |
| SCHEMBL18879037 | 0.61 | — | — | |
| SCHEMBL6818009 | 0.59 | MEN1 (0.38) | — | |
| SCHEMBL4238291 | 0.59 | CCNT1 (0.38) | PIM1 | |
| SCHEMBL31017312 | 0.57 | MAP4K4 (0.41) | — | |
| SCHEMBL6729678 | 0.56 | IDO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441339-A1 | Substituted triazolopyridazines | MERRELL PHARMACEUTICALS INC. (US) | 1991-08-14 | — | — | EP | disclosed |
| US-5011835-A | Substituted triazolopyridazines, pharmaceutical compositions and use | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-30 | — | — | US | disclosed |