SCHEMBL9853924

SCHEMBL9853924

O=C(Nc1ccn2c1CSC2c1cccnc1)c1cccc(C(=O)c2ccccc2)c1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854105 1.00 PTAFR (0.72) PTAFR
SCHEMBL9854104 0.93 PTAFR (0.67) PTAFR
SCHEMBL9854064 0.93 PTAFR (0.63) PTAFR
SCHEMBL9854079 0.93 PTAFR (0.63) PTAFR
SCHEMBL9854083 0.93 PTAFR (0.63) PTAFR
SCHEMBL9854149 0.93 PTAFR (0.63) PTAFR
SCHEMBL9853936 0.93 PTAFR (0.61) PTAFR
SCHEMBL9853930 0.91 PTAFR (0.64) PTAFR
SCHEMBL9854080 0.91 PTAFR (0.67) PTAFR
SCHEMBL9854025 0.91 PTAFR (0.60) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed