Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013129 | 0.89 | PTAFR (0.63) | PTAFRTBXAS1 | |
| SCHEMBL9853950 | 0.89 | PTAFR (0.57) | PTAFRALDH1A1TBXAS1 | |
| SCHEMBL9854020 | 0.88 | PTAFR (0.67) | PTAFRTBXAS1 | |
| SCHEMBL9853945 | 0.88 | PTAFR (0.56) | PTAFRTBXAS1 | |
| SCHEMBL9854024 | 0.86 | PTAFR (0.68) | PTAFRTBXAS1 | |
| SCHEMBL9854077 | 0.84 | PTAFR (0.58) | PTAFRTBXAS1 | |
| SCHEMBL9853993 | 0.84 | PTAFR (0.57) | PTAFRTBXAS1 | |
| SCHEMBL9854076 | 0.84 | PTAFR (0.57) | PTAFRMEN1ALDH1A1KMT2ATBXAS1 | |
| SCHEMBL9853930 | 0.84 | PTAFR (0.64) | PTAFRALDH1A1TBXAS1 | |
| SCHEMBL9853975 | 0.83 | PTAFR (0.54) | PTAFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |