Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854048 | 0.89 | PTAFR (0.58) | PTAFRPOLBTBXAS1 | |
| SCHEMBL9853922 | 0.88 | PTAFR (0.56) | PTAFRTBXAS1ALDH1A1 | |
| SCHEMBL9853990 | 0.88 | PTAFR (0.49) | PTAFRTBXAS1ALDH1A1 | |
| SCHEMBL9854080 | 0.86 | PTAFR (0.67) | PTAFR | |
| SCHEMBL9853992 | 0.85 | PTAFR (0.53) | PTAFRTBXAS1 | |
| SCHEMBL9854016 | 0.83 | PTAFR (0.49) | PTAFRTBXAS1 | |
| SCHEMBL9853956 | 0.82 | PTAFR (0.53) | PTAFRPOLBTBXAS1 | |
| SCHEMBL9854079 | 0.79 | PTAFR (0.63) | PTAFRTBXAS1TDP1 | |
| SCHEMBL9854083 | 0.79 | PTAFR (0.63) | PTAFRTBXAS1TDP1 | |
| SCHEMBL9853995 | 0.79 | PTAFR (0.58) | PTAFRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |