Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854149 | 0.90 | PTAFR (0.63) | PTAFRTBXAS1 | |
| SCHEMBL9853918 | 0.90 | PTAFR (0.59) | PTAFRTBXAS1 | |
| SCHEMBL9853936 | 0.90 | PTAFR (0.61) | PTAFRTBXAS1 | |
| SCHEMBL9854126 | 0.89 | PTAFR (0.54) | PTAFRTBXAS1 | |
| SCHEMBL9854014 | 0.89 | PTAFR (0.59) | PTAFRTBXAS1 | |
| SCHEMBL9854042 | 0.89 | PTAFR (0.58) | PTAFRTBXAS1GRM5CSF1R | |
| SCHEMBL9854048 | 0.89 | PTAFR (0.58) | PTAFRMEN1KMT2ATBXAS1LMNA | |
| SCHEMBL9853917 | 0.89 | PTAFR (0.58) | PTAFRTBXAS1 | |
| SCHEMBL9853995 | 0.89 | PTAFR (0.58) | PTAFRTBXAS1 | |
| SCHEMBL9853955 | 0.89 | PTAFR (0.58) | PTAFRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |