Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853954 | 1.00 | PTAFR (0.56) | PTAFRTBXAS1BRAFALDH1A1NPC1 | |
| SCHEMBL9853911 | 0.91 | PTAFR (0.56) | PTAFRTBXAS1ALDH1A1 | |
| SCHEMBL9853960 | 0.91 | PTAFR (0.56) | PTAFRTBXAS1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9854111 | 0.89 | PTAFR (0.55) | PTAFRTBXAS1 | |
| SCHEMBL9853908 | 0.89 | PTAFR (0.53) | PTAFRTBXAS1ALDH1A1NPC1RAB9A | |
| SCHEMBL9854002 | 0.89 | PTAFR (0.59) | PTAFRTBXAS1NPC1RAB9AMEN1 | |
| SCHEMBL9853951 | 0.89 | PTAFR (0.59) | PTAFRTBXAS1NPC1RAB9AMEN1 | |
| SCHEMBL9854056 | 0.89 | PTAFR (0.50) | PTAFRTBXAS1BRAFKMT2ATEK | |
| SCHEMBL9853956 | 0.88 | PTAFR (0.53) | PTAFRTBXAS1 | |
| SCHEMBL9853973 | 0.88 | PTAFR (0.49) | PTAFRTBXAS1BRAFALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |