SCHEMBL9854552

SCHEMBL9854552

Oc1cc(F)c(CCCc2c(F)cc(O)cc2F)c(F)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.70
SLC28A3 Q9HAS3 1/20 0.43
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
CYP19A1 P11511 1/20 0.36
BACE1 P56817 1/20 0.35
PTGS2 P35354 3/20 0.33
ESR1 P03372 3/20 0.33
ESR2 Q92731 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TYR P14679 1/20 0.32
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5642306 0.88 TAAR1 (0.61) TAAR1SLC28A3CA12CA1CA9
SCHEMBL24096195 0.82 TAAR1 (1.00) TAAR1CA12CA1CA9BACE1
SCHEMBL21082195 0.80 TAAR1 (0.64) TAAR1CA12CA1CA9CYP19A1
SCHEMBL23451053 0.80 TAAR1 (0.64) TAAR1CA12CA1CA9CYP19A1
SCHEMBL7911426 0.76 TAAR1 (0.58) TAAR1CA12CA1CA9CYP19A1
SCHEMBL4048403 0.76 TAAR1 (0.58) TAAR1CA12CA1CA9CYP19A1
SCHEMBL14793754 0.75 FFAR1 (0.57) TAAR1ALDH1A1HPGDNPSR1FFAR1
SCHEMBL16693755 0.74 TAAR1 (0.56) TAAR1CA12CA1CA9BACE1
SCHEMBL31652639 0.74 TAAR1 (0.70) TAAR1CA12CA1CA9BACE1
SCHEMBL16355888 0.73 TAAR1 (0.55) TAAR1ESR1ESR2FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0421416-A2 Heat fixable toner and heat fixing method CANON KABUSHIKI KAISHA (JP) 1991-04-10 EP disclosed