Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093854 | 1.00 | PPARA (0.56) | PPARASYKCTSSCTSKPPARG | |
| SCHEMBL30731784 | 1.00 | PPARA (0.56) | PPARASYKCTSSCTSKPPARG | |
| SCHEMBL1093849 | 1.00 | PPARA (0.56) | PPARASYKCTSSCTSKPPARG | |
| SCHEMBL186698 | 0.90 | SYK (0.56) | PPARASYKCTSSCTSKCTSL | |
| SCHEMBL5060739 | 0.90 | SYK (0.56) | PPARASYKCTSSCTSKCTSL | |
| SCHEMBL18526468 | 0.89 | PPARA (0.55) | PPARASYKCTSSCTSKPPARG | |
| SCHEMBL24946320 | 0.88 | PPARA (0.57) | PPARASYKCTSSCTSKPPARG | |
| SCHEMBL19400181 | 0.88 | PPARA (0.57) | PPARASYKCTSSCTSKPPARG | |
| SCHEMBL27685348 | 0.88 | PPARA (0.57) | PPARASYKCTSSCTSKPPARG | |
| SCHEMBL5343764 | 0.87 | CACNA1B (0.61) | PPARACTSSCTSKPPARGCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786163-B2 | Constrained cyano compounds | Forest Laboratories Holdings Limited (BM) | 2010-08-31 | — | — | US | disclosed |
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |