SCHEMBL9854811

SCHEMBL9854811

CC(C)(C)C(=O)CC(=O)C(C)(C)C.[U]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
HSD11B1 P28845 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
FFAR1 O14842 1/20 0.32
CPT2 P23786 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 2/20 0.31
VDR P11473 1/20 0.31
HIF1A Q16665 2/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7468545 1.00 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL93393 0.96 KMT2A (0.39) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL4837194 0.96 KMT2A (0.39) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL1318242 0.93 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL21405194 0.93 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL4778005 0.93 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL9325238 0.93 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL21002308 0.93 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL15788938 0.93 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1
SCHEMBL16267247 0.93 KMT2A (0.37) KMT2AHSD11B1NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442704-A2 Metal halide lamp and method of making the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-08-21 EP claimed
EP-0442704-A2 Metal halide lamp and method of making the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-08-21 EP disclosed