SCHEMBL9854843

SCHEMBL9854843

CCCc1ccc(C#Cc2ccc(OCC)cc2)nn1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACACB O00763 18/20 0.45
NQO1 P15559 1/20 0.41
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9855580 0.92 ACACB (0.44) ACACBNQO1MAPT
SCHEMBL9855069 0.90 ACACB (0.43) ACACBNQO1MAPT
SCHEMBL9855477 0.90 ACACB (0.45) ACACBMAPT
SCHEMBL9855520 0.90 ACACB (0.44) ACACB
SCHEMBL9855927 0.89 ACACB (0.42) ACACBNQO1MAPT
SCHEMBL9855585 0.89 ACACB (0.42) ACACBNQO1MAPT
SCHEMBL9855319 0.89 ACACB (0.42) ACACBNQO1MAPT
SCHEMBL9855292 0.88 APP (0.44) ACACBMAPT
SCHEMBL9855211 0.88 ACACB (0.44) ACACBNQO1
SCHEMBL9855370 0.87 NQO1 (0.54) ACACBNQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068053-A Liquid crystals for optical apparatus MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed