Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855141 | 0.81 | FFAR1 (0.42) | ACACBFFAR1MCHR1CHRNB2CHRNA4 | |
| SCHEMBL9855701 | 0.81 | APP (0.49) | GRM5KCNH2ACACBMCHR1 | |
| SCHEMBL24538232 | 0.80 | GRM5 (0.47) | GRM5KCNH2ADKCA12CA1 | |
| SCHEMBL9495233 | 0.80 | GRM5 (0.47) | GRM5ADKACACBMCHR1 | |
| SCHEMBL9855730 | 0.80 | ACACB (0.48) | ACACBMCHR1 | |
| SCHEMBL12353122 | 0.79 | GRM5 (0.59) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL14129682 | 0.79 | GRM5 (0.53) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL9855066 | 0.78 | FFAR1 (0.47) | ACACBFFAR1MCHR1 | |
| SCHEMBL9854970 | 0.77 | ACACB (0.47) | ACACBMCHR1CHRNB2CHRNA4 | |
| SCHEMBL9856080 | 0.77 | NPC1 (0.48) | ACACBMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |