SCHEMBL9855082

SCHEMBL9855082

CCCc1ccc(C#CC23CCC(c4ccc(CC)cc4)(CC2)CC3)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.34
ACACB O00763 5/20 0.34
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HTR1D P28221 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10511088 1.00 CYP2A6 (0.34) CYP2A6ACACBOPRM1OPRD1OPRK1
SCHEMBL10509106 1.00 CYP2A6 (0.34) CYP2A6ACACBOPRM1OPRD1OPRK1
SCHEMBL9855442 1.00 CYP2A6 (0.34) CYP2A6ACACBOPRM1OPRD1OPRK1
SCHEMBL9854990 0.96 ACACB (0.36) ACACBOPRM1OPRD1OPRK1OPRL1
SCHEMBL9855155 0.93 CYP2A6 (0.39) CYP2A6ACACBOPRM1OPRD1OPRK1
SCHEMBL10511152 0.92 ACACB (0.39) ACACB
SCHEMBL9855787 0.91 HSD17B10 (0.40)
SCHEMBL9855354 0.91 HSD17B10 (0.40)
SCHEMBL10510600 0.91 MEN1 (0.38) ACACB
SCHEMBL10510820 0.91 ACACB (0.42) ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068053-A Liquid crystals for optical apparatus MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed