SCHEMBL9855368

SCHEMBL9855368

CCCCOc1ccc(C#Cc2ccc(C#Cc3ccc(OCCCC)cc3)nn2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 4/20 0.51
CYP2D6 P10635 3/20 0.47
CYP3A4 P08684 1/20 0.47
MCHR1 Q99705 2/20 0.46
LTA4H P09960 3/20 0.46
CYP19A1 P11511 3/20 0.45
CYP2C9 P11712 3/20 0.45
CYP2C19 P33261 3/20 0.45
CYP1A2 P05177 2/20 0.45
NR5A1 Q13285 1/20 0.44
CHRNB2 P17787 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA7 P36544 1/20 0.44
CHRNA4 P43681 1/20 0.44
RAB9A P51151 3/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
NPC1 O15118 2/20 0.43
HSD17B10 Q99714 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854953 0.97 NR5A1 (0.50) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9855378 0.93 ACACB (0.49) ACACBMCHR1LTA4HCHRNB2CHRNB4
SCHEMBL9855090 0.92 ACACB (0.46) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9854938 0.91 ACACB (0.46) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9855048 0.91 ACACB (0.46) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9855477 0.89 ACACB (0.45) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9855008 0.89 ACACB (0.45) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9855280 0.88 ACACB (0.44) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9855341 0.88 ACACB (0.44) ACACBCYP2D6CYP3A4MCHR1LTA4H
SCHEMBL9855235 0.87 ACACB (0.43) ACACBCYP2D6CYP3A4MCHR1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068053-A Liquid crystals for optical apparatus MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed