Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | APEX1 | P27695 | 2/20 | 0.76 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634512 | 1.00 | POLB (0.76) | POLBAPEX1CTDSP1L3MBTL1PARP15 | |
| SCHEMBL11050987 | 1.00 | POLB (0.76) | POLBAPEX1CTDSP1L3MBTL1PARP15 | |
| SCHEMBL8899960 | 0.94 | POLB (0.69) | POLBAPEX1CTDSP1L3MBTL1PARP15 | |
| SCHEMBL7822703 | 0.91 | POLB (0.66) | POLBAPEX1CTDSP1L3MBTL1PARP15 | |
| SCHEMBL8827158 | 0.90 | POLB (0.68) | POLBAPEX1CTDSP1L3MBTL1PARP15 | |
| SCHEMBL5581302 | 0.87 | CA1 (0.67) | POLBAPEX1CTDSP1L3MBTL1SRD5A2 | |
| SCHEMBL22349 | 0.87 | CA1 (0.67) | POLBAPEX1CTDSP1L3MBTL1SRD5A2 | |
| SCHEMBL2917437 | 0.87 | CA1 (0.67) | POLBAPEX1CTDSP1L3MBTL1SRD5A2 | |
| SCHEMBL15708520 | 0.87 | APEX1 (1.00) | POLBAPEX1CTDSP1L3MBTL1PARP15 | |
| SCHEMBL8899969 | 0.87 | POLB (0.61) | POLBAPEX1CTDSP1L3MBTL1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255384-B1 | 4,4-BIS-(CARBOXYPHENYLSULFONYL)DIPHENYL ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | Tonen Corporation (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0255384-A1 | 4,4-bis-(carboxyphenylsulfonyl)diphenyl ethers, process for their preparation and their use | Tonen Corporation (JP) | 1988-02-03 | — | — | EP | disclosed |