Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854938 | 0.94 | ACACB (0.46) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9855378 | 0.91 | ACACB (0.49) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9855520 | 0.90 | ACACB (0.44) | ACACBMCHR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9855211 | 0.88 | ACACB (0.44) | ACACB | |
| SCHEMBL9855408 | 0.87 | ACACB (0.43) | ACACBMCHR1 | |
| SCHEMBL9855194 | 0.86 | ACACB (0.43) | ACACBMCHR1KDM4EALDH1A1HPGD | |
| SCHEMBL9855137 | 0.85 | ACACB (0.42) | ACACBMCHR1KDM4EALDH1A1HPGD | |
| SCHEMBL9855162 | 0.85 | ACACB (0.42) | ACACBMCHR1KDM4EALDH1A1HPGD | |
| SCHEMBL9855464 | 0.85 | ACACB (0.42) | ACACBMCHR1KDM4EALDH1A1HPGD | |
| SCHEMBL9855728 | 0.85 | APP (0.46) | ACACBMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |