Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.78 |
| ▸ | ERBB2 | P04626 | 19/20 | 0.78 |
| ▸ | ERBB3 | P21860 | 12/20 | 0.78 |
| ▸ | ERBB4 | Q15303 | 12/20 | 0.78 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.78 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.78 |
| ▸ | LCK | P06239 | 1/20 | 0.78 |
| ▸ | LYN | P07948 | 1/20 | 0.78 |
| ▸ | MET | P08581 | 1/20 | 0.78 |
| ▸ | CSK | P41240 | 1/20 | 0.78 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.78 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.78 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.78 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13042721 | 0.93 | EGFR (0.67) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| Tak-285 SCHEMBL29355721 | 0.88 | EGFR (1.00) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| Tak-285 SCHEMBL982278 | 0.88 | EGFR (1.00) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| Tak-285 SCHEMBL2747238 | 0.85 | EGFR (0.95) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| SCHEMBL20365459 | 0.82 | EGFR (0.91) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| SCHEMBL13226160 | 0.82 | EGFR (0.90) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| SCHEMBL2747601 | 0.82 | EGFR (0.90) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| Hydrochloric Acid SCHEMBL3506802 | 0.82 | EGFR (0.88) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| SCHEMBL2749509 | 0.81 | EGFR (0.85) | EGFRERBB2ERBB3ERBB4BMPR1B | |
| SCHEMBL2749523 | 0.81 | EGFR (0.90) | EGFRERBB2ERBB3ERBB4BMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003805-A1 | CONCOMITANT DRUG | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20110003805-A1 | CONCOMITANT DRUG | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20110003805-A1 | CONCOMITANT DRUG | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2255830-A1 | CONCOMITANT DRUG | Takeda Pharmaceutical Company Limited (JP) | 2010-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003805-A1 | CONCOMITANT DRUG | ERBB2, MTOR, ERBB4 | EGFR 6/4885ERBB2 1/4885ERBB3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.