Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | POLD1 | P28340 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.45 |
| ▸ | DTYMK | P23919 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856245 | 0.90 | POLG (0.56) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL9856088 | 0.90 | POLG (0.55) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL20906736 | 0.90 | POLG (0.55) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL3733569 | 0.90 | POLG (0.55) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL224861 | 0.90 | POLG (0.55) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL9856154 | 0.89 | POLG (0.54) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL14661236 | 0.88 | POLB (0.56) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL14661232 | 0.88 | POLB (0.56) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL8603553 | 0.86 | POLG (0.52) | POLGPOLBPOLA1POLD1P2RY2 | |
| SCHEMBL25752770 | 0.84 | POLG (0.50) | POLGPOLBPOLA1POLD1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |