Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126753 | 0.81 | KCNJ1 (0.58) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL3039451 | 0.79 | KCNJ1 (0.53) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL8439851 | 0.79 | KCNJ1 (0.61) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL9124661 | 0.78 | KCNJ1 (0.53) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8435792 | 0.78 | KCNJ1 (0.60) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5724126 | 0.78 | KCNJ1 (0.52) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL11658704 | 0.76 | IDO1 (0.51) | ALDH1A1HTR2ARAB9A | |
| SCHEMBL6943478 | 0.75 | DPP8 (0.61) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL9661798 | 0.75 | KCNJ1 (0.49) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL9782567 | 0.74 | IDO1 (0.56) | ALDH1A1MAPTHTR2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443883-A1 | Carbapenem derivatives having antibiotic activity, their preparation and their use | Sankyo Company Limited (JP) | 1991-08-28 | — | — | EP | disclosed |