Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368632 | 1.00 | KMT2A (0.44) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL5548291 | 0.91 | SIRT2 (0.45) | KMT2AMEN1NPC1ALDH1A1SIRT2 | |
| SCHEMBL901541 | 0.86 | MME (0.45) | POLBLMNASIRT2SIRT1TGM2 | |
| SCHEMBL901542 | 0.86 | MME (0.45) | POLBLMNASIRT2SIRT1TGM2 | |
| SCHEMBL15101628 | 0.86 | MME (0.45) | POLBLMNASIRT2SIRT1TGM2 | |
| SCHEMBL5346764 | 0.82 | SMN1; SMN2 (0.46) | KMT2AMEN1POLBLMNASIRT2 | |
| SCHEMBL3368639 | 0.78 | KMT2A (0.43) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL9856515 | 0.78 | KMT2A (0.43) | KMT2AMEN1NPC1NPSR1POLB | |
| SCHEMBL21373191 | 0.78 | MME (0.46) | KMT2APOLBLMNASIRT2SIRT1 | |
| SCHEMBL30313716 | 0.78 | MME (0.46) | KMT2APOLBLMNASIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239062-B1 | N2-(1-CARBOXY-3-OXO-3-PHENYLPROPYL)-L-LYSINE COMPOUNDS AND THEIR DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-29 | — | — | EP | disclosed |