Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TYMP | P19971 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855806 | 0.91 | PNP (0.47) | POLBTYMPPNPGSK3ARPS6KA3 | |
| SCHEMBL5360855 | 0.91 | POLB (0.62) | POLBTYMPPNPGSK3ARPS6KA3 | |
| SCHEMBL10532094 | 0.85 | POLB (0.53) | POLBTYMPPNPGSK3ARPS6KA3 | |
| SCHEMBL10006936 | 0.82 | POLB (0.67) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL1401380 | 0.82 | POLB (0.56) | POLBTYMPPNPP2RY2P2RY4 | |
| SCHEMBL7519500 | 0.82 | PNP (0.50) | POLBTYMPPNPHINT1NT5E | |
| SCHEMBL13031161 | 0.82 | TYMP (0.53) | POLBTYMPPNPGSK3ARPS6KA3 | |
| SCHEMBL7519498 | 0.82 | PNP (0.50) | POLBTYMPPNPHINT1NT5E | |
| SCHEMBL16160872 | 0.81 | POLB (0.57) | POLBTYMPPNPP2RY2P2RY4 | |
| SCHEMBL338780 | 0.81 | POLB (0.60) | POLBTYMPGSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |