Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.80 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.80 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.80 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.80 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.80 |
| ▸ | RAF1 | P04049 | 3/20 | 0.80 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.67 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.67 |
| ▸ | GCGR | P47871 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | FRK | P42685 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.48 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857456 | 0.94 | CSNK1A1 (0.75) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL19868972 | 0.90 | MAPK14 (0.97) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL19869014 | 0.89 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL1387706 | 0.87 | CSNK1D (0.88) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL4587083 | 0.82 | MAPK11 (1.00) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL4024638 | 0.82 | MAPK11 (1.00) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL19869015 | 0.81 | MAPK13 (0.77) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL4026830 | 0.81 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL9517058 | 0.81 | RAF1 (0.62) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| Hydrochloric Acid SCHEMBL4032200 | 0.80 | MAPK14 (0.98) | MAPK13MAPK12MAPK11MAPK14MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436851-A1 | Compounds active as inhibitors of the enzyme HMG-CoA reductase and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1991-07-17 | — | — | EP | disclosed |