SCHEMBL9857533

SCHEMBL9857533

S=C=Nc1ccc(OBOc2ccc(N=C=S)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 3/20 0.50
MIF P14174 2/20 0.50
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HSD17B10 Q99714 3/20 0.38
PNMT P11086 1/20 0.33
KDM4E B2RXH2 2/20 0.33
USP2 O75604 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LTA P01374 2/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
P2RX3 P56373 2/20 0.33
RAD51 Q06609 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
RAD1 O60671 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3914324 0.80 CYP3A4 (0.48) P2RY6CA1CA2CYP3A4TDP1
Bitoscanate SCHEMBL157128 0.80 MIF (0.72) P2RY6MIFCA1CA2HSD17B10
SCHEMBL941550 0.78 MIF (0.56) P2RY6MIFCA1CA2HSD17B10
SCHEMBL9857139 0.78 MIF (0.47) P2RY6MIFCA1CA2HSD17B10
SCHEMBL40681 0.74 MIF (0.53) P2RY6MIFCA1CA2KDM4E
SCHEMBL1548531 0.72 MIF (0.62) P2RY6MIFCA1CA2HSD17B10
SCHEMBL3823434 0.71 MIF (0.67) P2RY6MIFCA1CA2HSD17B10
SCHEMBL5501717 0.71 P2RY6 (0.48) P2RY6MIFCA1CA2HSD17B10
SCHEMBL1588318 0.71 P2RY6 (0.48) P2RY6MIFCA1CA2HSD17B10
SCHEMBL10711773 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452858-A2 Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds BRACCO INTERNATIONAL B.V. (NL) 1991-10-23 EP claimed