Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.74 |
| ▸ | PPARA | Q07869 | 17/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 14/20 | 0.74 |
| ▸ | PTGES | O14684 | 12/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613848 | 0.95 | PPARG (0.81) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613827 | 0.90 | PPARG (0.73) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614203 | 0.89 | PPARG (0.72) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613814 | 0.89 | PPARG (0.72) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9858491 | 0.89 | PPARG (0.75) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9858468 | 0.88 | PPARG (0.74) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL10420826 | 0.87 | PPARG (0.59) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614105 | 0.86 | PPARG (0.63) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL6935114 | 0.83 | PPARG (0.65) | PPARGPPARAALOX5PTGES | |
| SCHEMBL6930527 | 0.82 | PPARG (0.67) | PPARGPPARAALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |