SCHEMBL9858105

SCHEMBL9858105

CCN1C(=O)/C(=C2\Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 14/20 1.00
▸ KMT2A Q03164 14/20 1.00
▸ POLB P06746 8/20 1.00
▸ MAPT P10636 8/20 1.00
▸ MMP13 P45452 4/20 1.00
▸ HPGD P15428 4/20 0.91
▸ ALOX15 P16050 3/20 0.91
▸ ALOX12 P18054 3/20 0.91
▸ CASP1 P29466 3/20 0.91
▸ HSD17B10 Q99714 3/20 0.91
▸ CASP7 P55210 2/20 0.91
▸ LMNA P02545 1/20 0.91
▸ CTDSP1 Q9GZU7 2/20 0.73
▸ RXFP1 Q9HBX9 1/20 0.73
▸ ALDH1A1 P00352 7/20 0.68
▸ L3MBTL1 Q9Y468 1/20 0.68
▸ TDP1 Q9NUW8 4/20 0.63
▸ PKM P14618 1/20 0.63
▸ SMN1; SMN2 Q16637 3/20 0.61
▸ MAPK1 P28482 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858108 1.00 MEN1 (1.00) MEN1KMT2APOLBMAPTMMP13
SCHEMBL10786670 0.95 MEN1 (1.00) MEN1KMT2APOLBMAPTMMP13
SCHEMBL11207327 0.89 MEN1 (0.81) MEN1KMT2APOLBMAPTMMP13
SCHEMBL6264761 0.89 MEN1 (0.81) MEN1KMT2APOLBMAPTMMP13
SCHEMBL10713249 0.88 MEN1 (0.79) MEN1KMT2APOLBMAPTMMP13
SCHEMBL8863661 0.88 MEN1 (0.86) MEN1KMT2APOLBMAPTMMP13
SCHEMBL8863662 0.88 MEN1 (0.86) MEN1KMT2APOLBMAPTMMP13
SCHEMBL30000370 0.85 MEN1 (0.78) MEN1KMT2APOLBMAPTMMP13
SCHEMBL194201 0.85 MEN1 (0.78) MEN1KMT2APOLBMAPTMMP13
SCHEMBL194200 0.85 MEN1 (0.78) MEN1KMT2APOLBMAPTMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233396-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (4) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-07-31 — — EP claimed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 — — US claimed
EP-0233396-A2 Silver halide photographic emulsions with novel grain faces (4) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-08-26 — — EP claimed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 — — US disclosed
US-4680256-A Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 — — US disclosed
EP-0034279-B1 SULFOALKYLATING AGENTS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE MANUFACTURE OF QUANTERNARY SULFOALKYL SALTS Agfa-Gevaert AG (DE) 1983-06-22 — — EP disclosed
EP-0034279-A2 Sulfoalkylating agents, process for their preparation and their use in the manufacture of quanternary sulfoalkyl salts Agfa-Gevaert AG (DE) 1981-08-26 — — EP disclosed
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