Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 5/20 | 0.46 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 10/20 | 0.44 |
| ▸ | HTR7 | P34969 | 10/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9858320 | 0.99 | CHRM3 (0.56) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL6542148 | 0.84 | CHRM3 (0.61) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL8877360 | 0.81 | CHRM3 (0.61) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL14591308 | 0.74 | CHRM3 (0.69) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL9200347 | 0.74 | CHRM3 (0.59) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL5361640 | 0.73 | CHRM3 (0.67) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6542162 | 0.73 | CHRM3 (0.67) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL6540873 | 0.73 | CHRM3 (0.67) | CHRM3CHRM2CHRM1DRD2DRD4 | |
| SCHEMBL8891132 | 0.73 | CHRM3 (1.00) | CHRM3CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL9200359 | 0.73 | CHRM3 (0.67) | CHRM3CHRM2CHRM1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447727-A1 | Novel 8-sulfamylmethylene-2-amino tetralins | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-09-25 | — | — | EP | disclosed |