Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859555 | 1.00 | PTAFR (1.00) | PTAFR | |
| SCHEMBL8752379 | 1.00 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9689913 | 0.98 | PTAFR (0.96) | PTAFR | |
| SCHEMBL9689918 | 0.98 | PTAFR (0.96) | PTAFR | |
| SCHEMBL9689907 | 0.98 | PTAFR (0.96) | PTAFR | |
| SCHEMBL9689973 | 0.94 | PTAFR (0.89) | PTAFR | |
| SCHEMBL9689979 | 0.94 | PTAFR (0.89) | PTAFR | |
| SCHEMBL9689982 | 0.94 | PTAFR (0.89) | PTAFR | |
| SCHEMBL10429157 | 0.93 | PTAFR (0.86) | PTAFR | |
| SCHEMBL10429156 | 0.93 | PTAFR (0.86) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010100-A | Skeletal muscular disorders, hydertensive agents, cardiovascular disorders | MERCK & CO. INC. (US) | 1991-04-23 | — | — | US | claimed |
| US-5010100-A | Skeletal muscular disorders, hydertensive agents, cardiovascular disorders | MERCK & CO. INC. (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0322033-A2 | New 2,5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1989-06-28 | — | — | EP | disclosed |