Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.63 |
| ▸ | ESRRG | P62508 | 11/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859690 | 1.00 | ESR1 (0.63) | ESR1ESR2ESRRGNR4A1NR4A2 | |
| SCHEMBL9859681 | 1.00 | ESR1 (0.63) | ESR1ESR2ESRRGNR4A1NR4A2 | |
| SCHEMBL8366275 | 0.96 | ESR1 (0.67) | ESR1ESR2ESRRGCYP19A1LMNA | |
| SCHEMBL9097507 | 0.96 | ESR1 (0.67) | ESR1ESR2ESRRGCYP19A1LMNA | |
| SCHEMBL8366276 | 0.96 | ESR1 (0.67) | ESR1ESR2ESRRGCYP19A1LMNA | |
| SCHEMBL8364891 | 0.94 | ESR1 (0.65) | ESR1ESR2ESRRGNR4A1NR4A2 | |
| SCHEMBL8364894 | 0.94 | ESR1 (0.65) | ESR1ESR2ESRRGNR4A1NR4A2 | |
| SCHEMBL8367728 | 0.91 | ESR1 (0.60) | ESR1ESR2ESRRGCYP19A1ESRRB | |
| SCHEMBL8367727 | 0.91 | ESR1 (0.60) | ESR1ESR2ESRRGCYP19A1ESRRB | |
| SCHEMBL8368223 | 0.89 | ESR1 (0.58) | ESR1ESR2ESRRGNR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996225-A | Antitumor agents | FARMOS GROUP LTD. (FI) | 1991-02-26 | — | — | US | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |