Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923422 | 0.92 | MEN1 (0.47) | MEN1KMT2AKDM4CPOLBNPC1 | |
| SCHEMBL9860185 | 0.91 | MEN1 (0.46) | MEN1KMT2AKDM4CPOLBNPC1 | |
| SCHEMBL10807959 | 0.89 | MEN1 (0.38) | MEN1KMT2AKDM4CPOLBNPC1 | |
| SCHEMBL9860242 | 0.88 | MEN1 (0.46) | MEN1KMT2AKDM4CPOLBNPC1 | |
| SCHEMBL10803495 | 0.86 | MEN1 (0.37) | MEN1KMT2AKDM4CPOLBDHFR | |
| SCHEMBL5725898 | 0.86 | MEN1 (0.39) | MEN1KMT2AKDM4CPOLBACP1 | |
| SCHEMBL10916857 | 0.84 | MEN1 (0.41) | MEN1KMT2AKDM4CPOLBACP1 | |
| SCHEMBL5725731 | 0.81 | MEN1 (0.39) | MEN1KMT2AKDM4CPOLBNPC1 | |
| SCHEMBL5725631 | 0.81 | NPSR1 (0.36) | MEN1KMT2APOLBACP1L3MBTL1 | |
| SCHEMBL10923424 | 0.81 | MEN1 (0.41) | MEN1KMT2AKDM4CPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996225-A | Antitumor agents | FARMOS GROUP LTD. (FI) | 1991-02-26 | — | — | US | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |