Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19199596 | 0.81 | NSD2 (0.56) | MAPTTDP1ALDH1A1KMT2APRSS1 | |
| SCHEMBL1793103 | 0.76 | TRPV1 (0.56) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1789755 | 0.76 | CYP4F2 (0.55) | MAPTTDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11509379 | 0.75 | MAPT (0.47) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28397891 | 0.74 | TYR (0.43) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1789266 | 0.74 | HPGD (0.51) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28407107 | 0.73 | TYR (0.42) | ALDH1A1PRSS1ACRSMN1; SMN2LMNA | |
| SCHEMBL9558835 | 0.72 | KMT2A (0.50) | MAPTKMT2APRSS1ACRSMN1; SMN2 | |
| SCHEMBL28401256 | 0.72 | TYR (0.41) | PRSS1ACRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5706230 | 0.72 | KMT2A (0.70) | MAPTKMT2APRSS1ACRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003123-A | Process for the preparation of cyclobutenoarenes | SHELL OIL COMPANY (US) | 1991-03-26 | — | — | US | disclosed |