Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296576 | 0.84 | PDE4A (0.64) | PDE4AKDM4EGAAHDAC3HDAC1 | |
| SCHEMBL11272756 | 0.75 | IDH1 (0.43) | PDE4AKDM4EGAAHTTALDH1A1 | |
| SCHEMBL6640516 | 0.74 | PDE4A (0.55) | PDE4AKDM4EGAAHDAC1HTT | |
| SCHEMBL17070790 | 0.74 | PDE4A (0.55) | PDE4AKDM4EGAAHDAC3HDAC1 | |
| SCHEMBL5033894 | 0.74 | PDE4A (0.76) | PDE4AKDM4EGAAHDAC3HDAC1 | |
| SCHEMBL18163295 | 0.74 | PDE4A (0.76) | PDE4AKDM4EGAAHDAC3HDAC1 | |
| SCHEMBL21260553 | 0.74 | PDE4A (0.76) | PDE4AKDM4EGAAHDAC3HDAC1 | |
| SCHEMBL12645185 | 0.74 | PDE4A (0.55) | PDE4AKDM4EGAAHDAC3HDAC1 | |
| SCHEMBL21260552 | 0.74 | PDE4A (0.76) | PDE4AKDM4EGAAHDAC3HDAC1 | |
| SCHEMBL20402878 | 0.74 | PDE4A (0.82) | PDE4AKDM4EGAAHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981964-A | PHOTOSTABILIZERS | ICI AMERICAS INC. (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0373892-A1 | Tetramethyl piperidyl terminated triazine oligomeric esters and amides | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0373839-A1 | Oligomeric polyesters and polyamides containing dipiperidyl triazine groups | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| US-4889882-A | RADIATION RESISTANCE, PHOTOSTABILITY POLYMER ADDITIVE | ICI AMERICAS INC. (US) | 1989-12-26 | — | — | US | disclosed |