Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862568 | 1.00 | TRPV1 (0.43) | TRPV1EPHX2MAPTGAATLR7 | |
| SCHEMBL9862610 | 0.81 | TRPV1 (0.41) | TRPV1EPHX2MAPTGAATLR7 | |
| SCHEMBL9862639 | 0.81 | TRPV1 (0.41) | TRPV1EPHX2MAPTGAATLR7 | |
| SCHEMBL9862423 | 0.79 | GRIN2B (0.41) | TRPV1EPHX2MAPTGAAGRIN2B | |
| SCHEMBL9862432 | 0.79 | GRIN2B (0.41) | TRPV1EPHX2MAPTGAAGRIN2B | |
| SCHEMBL9862695 | 0.77 | NQO1 (0.47) | NPC1RAB9AMAOBKMT2A | |
| SCHEMBL9862696 | 0.77 | NQO1 (0.47) | NPC1RAB9AMAOBKMT2A | |
| SCHEMBL15137388 | 0.74 | CES1 (0.46) | NPC1RAB9A | |
| SCHEMBL15137342 | 0.74 | CES1 (0.46) | NPC1RAB9A | |
| SCHEMBL15137389 | 0.74 | CES1 (0.46) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4891450-A | FLUORINE-CONTAINING ARYLALKENES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-02 | — | — | US | claimed |
| US-4988826-A | Fluoroalkylstyrene derivatives as intermediates for insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-29 | — | — | US | disclosed |
| US-4891450-A | FLUORINE-CONTAINING ARYLALKENES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-02 | — | — | US | disclosed |
| EP-0280383-A1 | Process for intermediates for insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-31 | — | — | EP | disclosed |