Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986750 | 1.00 | EGFR (0.33) | EGFRKDM4EMEN1MAPTKMT2A | |
| SCHEMBL10327133 | 0.89 | EGFR (0.34) | EGFR | |
| SCHEMBL10326926 | 0.89 | EGFR (0.34) | EGFR | |
| SCHEMBL987772 | 0.89 | EGFR (0.34) | EGFR | |
| SCHEMBL987774 | 0.89 | EGFR (0.34) | EGFR | |
| SCHEMBL10326928 | 0.88 | EGFR (0.33) | EGFR | |
| SCHEMBL1654858 | 0.87 | — | — | |
| SCHEMBL984091 | 0.82 | — | — | |
| SCHEMBL10326925 | 0.82 | — | — | |
| SCHEMBL2040835 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454223-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE DERIVATIVES | Syngenta Limited (GB) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011007146-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2011-01-20 | — | — | WO | disclosed |