SCHEMBL9863103

SCHEMBL9863103

C1=C(C2=CCCCCC2)CCCCC1.C[SiH](Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TYMP P19971 2/20 0.42
TDP1 Q9NUW8 1/20 0.34
PSMB5 P28074 8/20 0.34
PTGS2 P35354 1/20 0.34
PSMB1 P20618 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ELANE P08246 1/20 0.33
ACMSD Q8TDX5 1/20 0.33
JAK2 O60674 1/20 0.32
JAK1 P23458 1/20 0.32
JAK3 P52333 1/20 0.32
CXCR3 P49682 1/20 0.32
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18244172 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL3796623 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL3233355 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL2105114 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL21057468 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL11201526 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL18244171 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL3233362 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL3502363 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1
SCHEMBL119773 0.84 TYMP (0.41) TYMPTDP1PSMB5PTGS2PSMB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3275649-B1 RESIN MOLDED BODY AND METHOD FOR PRODUCING SAME RIMTEC CORP (JP) 2021-07-14 EP disclosed
EP-2902428-B1 POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCING RESIN MOLDED ARTICLE RIMTEC CORP (JP) 2020-08-12 EP disclosed
US-10611866-B2 Norbornene cross-linked polymer and method for producing same RIMTEC CORPORATION (JP) 2020-04-07 US disclosed
US-20190169329-A1 NORBORNENE CROSS-LINKED POLYMER AND METHOD FOR PRODUCING SAME RIMTEC CORPORATION (JP) 2019-06-06 US disclosed
US-20180319912-A1 NORBORNENE CROSS-LINKED POLYMER AND METHOD FOR PRODUCING SAME RIMTEC CORPORATION (JP) 2018-11-08 US disclosed
EP-3275649-A1 RESIN MOLDED BODY AND METHOD FOR PRODUCING SAME Rimtec Corporation (JP) 2018-01-31 EP disclosed
US-20180022882-A1 RESIN MOLDED BODY AND METHOD FOR PRODUCING SAME RIMTEC CORPORATION (JP) 2018-01-25 US disclosed
US-9777086-B2 Polymerizable composition and method of production of resin shaped article RIMTEC CORPORATION (JP) 2017-10-03 US disclosed
US-20160244540-A1 NORBORNENE CROSS-LINKED POLYMER AND METHOD FOR PRODUCING SAME RIMTEC CORPORATION (JP) 2016-08-25 US disclosed
EP-3031841-A1 NORBORNENE CROSS-LINKED POLYMER AND METHOD FOR PRODUCING SAME Rimtec Corporation (JP) 2016-06-15 EP disclosed
US-20150240007-A1 POLYMERIZABLE COMPOSITION AND METHOD OF PRODUCTION OF RESIN SHAPED ARTICLE RIMTEC CORPORATION (JP) 2015-08-27 US disclosed
EP-2902428-A1 POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCING RESIN MOLDED ARTICLE Rimtec Corporation (JP) 2015-08-05 EP disclosed
US-5063103-A Ring-opening polymerization of norbornenes in mold in presence of glass mat bonded with polyolefins and/or vinylaromatic polymers, metathesis system catalysts and cocatalysts NIPPON ZEON CO., LTD. (JP) 1991-11-05 US disclosed
EP-0347819-A2 Reinforced polymeric matrix NIPPON ZEON CO., LTD. (JP) 1989-12-27 EP disclosed