Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.31 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.31 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.31 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666442 | 1.00 | KCNH2 (0.36) | KCNH2HRH3SCARB1PYCR1HDAC6 | |
| SCHEMBL9668318 | 0.86 | KCNH2 (0.50) | KCNH2HRH3SCARB1HDAC6LTA4H | |
| SCHEMBL9705718 | 0.86 | KCNH2 (0.50) | KCNH2HRH3SCARB1HDAC6LTA4H | |
| Disoxaril SCHEMBL147146 | 0.86 | KCNH2 (0.50) | KCNH2HRH3SCARB1HDAC6LTA4H | |
| SCHEMBL9666409 | 0.86 | KCNH2 (0.50) | KCNH2HRH3SCARB1HDAC6LTA4H | |
| SCHEMBL9862904 | 0.85 | KCNH2 (0.35) | KCNH2HRH3SCARB1LTA4HMEN1 | |
| SCHEMBL9666126 | 0.85 | KCNH2 (0.51) | KCNH2HRH3SCARB1HDAC6LTA4H | |
| SCHEMBL10419450 | 0.83 | PPARA (0.38) | HDAC6 | |
| SCHEMBL9862970 | 0.83 | KCNH2 (0.32) | KCNH2HRH3SCARB1 | |
| SCHEMBL9705792 | 0.82 | PDE10A (0.33) | HDAC6NR1I2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |