Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657827 | 0.98 | GSK3B (0.66) | GSK3BCA1CA2ALDH1A1HIF1A | |
| Phenacyl Chloride SCHEMBL10545849 | 0.85 | GSK3B (0.70) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| SCHEMBL11983785 | 0.81 | GSK3B (0.70) | GSK3BCA1CA2ALDH1A1MAPK1 | |
| SCHEMBL11480265 | 0.80 | GSK3B (0.80) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| SCHEMBL319223 | 0.79 | GSK3B (0.68) | GSK3BCA1CA2ALDH1A1RAB9A | |
| SCHEMBL3303569 | 0.78 | GSK3B (0.56) | GSK3BCA1CA2ALDH1A1RAB9A | |
| SCHEMBL8286989 | 0.78 | GSK3B (0.66) | GSK3BCA1CA2ALDH1A1RAB9A | |
| SCHEMBL10222530 | 0.78 | GSK3B (0.66) | GSK3BCA1CA2ALDH1A1RAB9A | |
| SCHEMBL250688 | 0.78 | GSK3B (1.00) | GSK3BCA1CA2ALDH1A1RAB9A | |
| SCHEMBL13545641 | 0.78 | GSK3B (0.66) | GSK3BCA1CA2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041567-A | Human and veterianary medicine; veneral diseases respiratory diseases, bovine mastitis | BEECHAM GROUP PLC (GB) | 1991-08-20 | — | — | US | disclosed |
| US-4812470-A | Antibacterial monic acid derivatives | BEECHAM GROUP P.L.C. (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0087953-B1 | ANTIBACTERIAL 1-NORMON-2-YL-HETEROCYCLIC COMPOUNDS | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |
| EP-0087953-A2 | Antibacterial 1-normon-2-yl-heterocyclic compounds | BEECHAM GROUP PLC (GB) | 1983-09-07 | — | — | EP | disclosed |