Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863402 | 0.91 | TLR2 (0.49) | TLR2SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL9576035 | 0.91 | TLR2 (0.49) | TLR2SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL9863484 | 0.89 | TLR2 (0.48) | TLR2SMN1; SMN2LMNANPC1RAB9A | |
| Iodide SCHEMBL9864526 | 0.88 | TLR2 (0.47) | TLR2 | |
| Hydrochloric Acid SCHEMBL9863601 | 0.88 | TLR2 (0.47) | TLR2SMN1; SMN2LMNA | |
| SCHEMBL10833466 | 0.84 | HTT (0.51) | HTT | |
| SCHEMBL31613224 | 0.83 | HTT (0.52) | SMN1; SMN2LMNAHTTMAPTL3MBTL1 | |
| SCHEMBL9863436 | 0.82 | TLR2 (0.44) | TLR2SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL9766536 | 0.82 | TLR2 (0.49) | TLR2 | |
| SCHEMBL10604671 | 0.81 | PLA2G10 (0.47) | TLR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025005-A | Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-4737518-A | ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-12 | — | — | US | disclosed |