Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827796 | 0.81 | CRBN (0.70) | CYP19A1POLBDDB1CRBN | |
| SCHEMBL14264660 | 0.81 | CYP19A1 (0.59) | CYP19A1MAPTLMNAPKMNPC1 | |
| SCHEMBL21886107 | 0.81 | TP53 (0.50) | CYP19A1MAPTLMNAPKMNPC1 | |
| SCHEMBL24204350 | 0.81 | CYP19A1 (0.68) | CYP19A1MAPTLMNAPKMNPC1 | |
| SCHEMBL28509512 | 0.81 | CYP19A1 (0.68) | CYP19A1MAPTLMNAPKMNPC1 | |
| SCHEMBL3274268 | 0.81 | CYP19A1 (1.00) | CYP19A1MAPTLMNAPKMNPC1 | |
| SCHEMBL1567424 | 0.80 | DDB1 (0.67) | CYP19A1MAPTLMNAPKMNPC1 | |
| SCHEMBL8300066 | 0.80 | DDB1 (0.67) | CYP19A1MAPTLMNAPKMNPC1 | |
| Methane SCHEMBL7953352 | 0.78 | DDB1 (0.65) | CYP19A1MAPTLMNAPKMNPC1 | |
| SCHEMBL31633556 | 0.77 | DDB1 (0.69) | CYP19A1MAPTLMNAPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438240-A2 | Imidized segmented copolymers | ROHM AND HAAS COMPANY (US) | 1991-07-24 | — | — | EP | disclosed |