⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15862754 | 0.78 | — | — | |
| SCHEMBL5583558 | 0.72 | — | — | |
| SCHEMBL443371 | 0.67 | — | — | |
| SCHEMBL4511207 | 0.67 | — | — | |
| SCHEMBL2616428 | 0.66 | — | — | |
| Ammonia Solution, Strong SCHEMBL9520449 | 0.65 | — | — | |
| SCHEMBL6946235 | 0.63 | — | — | |
| SCHEMBL9116646 | 0.63 | — | — | |
| SCHEMBL27984046 | 0.62 | — | — | |
| SCHEMBL13974149 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122334-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2016-05-05 | — | — | US | disclosed |
| US-9266866-B2 | Inhibitors of C-FMS kinase | JANSSEN PHARMACEUTICA NV (BE) | 2016-02-23 | — | — | US | disclosed |
| US-20140200245-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2014-07-17 | — | — | US | disclosed |
| US-5055125-A | Thiocarbamates with dithiocarbamic acid derivatives | NITROKEMIA IPARTELEPEK (HU) | 1991-10-08 | — | — | US | disclosed |
| CN-1047958-A | The herbicidal composition and the antidotes composition of detoxifcation | NITROKEMIA IPARTELEPEK (HU) | 1990-12-26 | — | — | CN | disclosed |