Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 9/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343588 | 0.81 | PNP (1.00) | PNP | |
| SCHEMBL9217412 | 0.79 | PNP (0.72) | PNP | |
| SCHEMBL6345482 | 0.78 | PNP (1.00) | PNP | |
| SCHEMBL9073809 | 0.78 | PNP (0.73) | PNP | |
| SCHEMBL6343921 | 0.77 | PNP (1.00) | PNP | |
| SCHEMBL15628192 | 0.77 | PNP (0.65) | PNP | |
| SCHEMBL6340454 | 0.77 | PNP (1.00) | PNP | |
| SCHEMBL6353279 | 0.77 | PNP (0.65) | PNP | |
| SCHEMBL6344169 | 0.77 | PNP (0.65) | PNP | |
| SCHEMBL6342372 | 0.76 | PNP (0.76) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008270-A | 2-amino-7-(heterocyclomethyl)-3H,5H-pyrrolo[3,2-d]pyrimidin-4-ones and pharmaceutical uses and compositions containing the same | BIOCRYST, INC. (US) | 1991-04-16 | — | — | US | disclosed |