Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684206 | 0.88 | GLP1R (0.40) | HPGDHSD17B10ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8855508 | 0.79 | GRIN2D (0.47) | HPGDHSD17B10ALDH1A1ALOX15NPSR1 | |
| SCHEMBL7045388 | 0.79 | NPSR1 (0.44) | HPGDHSD17B10ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8183606 | 0.79 | HSD17B10 (0.44) | HPGDHSD17B10ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL30569300 | 0.77 | HPGD (0.41) | HPGDHSD17B10ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7043132 | 0.75 | GRIN2D (0.39) | HPGDHSD17B10CYP1A2HTTGRIN2D | |
| SCHEMBL31730671 | 0.75 | GRIN2D (0.39) | HPGDHSD17B10CYP1A2HTTGRIN2D | |
| SCHEMBL5987289 | 0.74 | AR (0.62) | HPGDHSD17B10ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8116479 | 0.73 | NPSR1 (0.37) | HPGDHSD17B10ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8873028 | 0.72 | GRIN2D (0.37) | HPGDHSD17B10ALDH1A1HTTGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4724234-A | ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION | THERAPEUTICAL SYSTEMS CORP. (US) | 1988-02-09 | — | — | US | disclosed |
| US-4031107-A | Method for introducing amino groups into benzimidazole or imidazopyridine compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-3988465-A | HERBICIDES | SHELL OIL COMPANY (US) | 1976-10-26 | — | — | US | disclosed |