SCHEMBL9866066

SCHEMBL9866066

COc1nc2cccccc-2n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
TSHR P16473 2/20 0.68
ATM Q13315 2/20 0.68
MAPT P10636 1/20 0.68
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 2/20 0.52
HPGD P15428 2/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPK1 P28482 2/20 0.52
HTT P42858 2/20 0.52
USP2 O75604 1/20 0.52
CA4 P22748 2/20 0.43
POLB P06746 1/20 0.43
PRNP P04156 1/20 0.41
MAT2A P31153 1/20 0.41
RAB9A P51151 2/20 0.40
CCR1 P32246 2/20 0.40
CCR8 P51685 2/20 0.40
CA12 O43570 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15080589 0.75 MEN1 (0.79) MEN1KMT2ATSHRATMMAPT
SCHEMBL2136335 0.75 MEN1 (0.79) MEN1KMT2ATSHRATMMAPT
SCHEMBL21379837 0.74 MEN1 (0.76) MEN1KMT2ATSHRATMMAPT
SCHEMBL14393036 0.74 MEN1 (0.76) MEN1KMT2ATSHRATMMAPT
SCHEMBL3306611 0.74 MEN1 (0.76) MEN1KMT2ATSHRATMMAPT
SCHEMBL5198118 0.73 KMT2A (0.64) MEN1KMT2ATSHRATMMAPT
SCHEMBL1130501 0.73 KMT2A (0.61) MEN1KMT2ATSHRATMMAPT
SCHEMBL19023810 0.73 KMT2A (0.61) MEN1KMT2ATSHRATMMAPT
SCHEMBL2035174 0.72 MEN1 (0.63) MEN1KMT2ATSHRATMMAPT
SCHEMBL11269321 0.71 MAPT (0.61) MEN1KMT2ATSHRATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5003077-A Having a cycloheptimidazole nucleus; photostability; methine bond having an auxochrome FUJI PHOTO FILM CO., LTD. (JP) 1991-03-26 US disclosed
US-4900648-A RECORDING, ERASING USING LASER BEAM, METHINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1990-02-13 US disclosed
US-4814265-A CONTAINING METHANE DYE FUJI PHOTO FILM CO., LTD. (JP) 1989-03-21 US disclosed