Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391106 | 0.99 | CA1 (0.62) | CA1CA2SMN1; SMN2HTTNPC1 | |
| SCHEMBL29459203 | 0.92 | CA1 (0.58) | CA1CA2SMN1; SMN2HTTNPC1 | |
| SCHEMBL10169791 | 0.92 | CA1 (0.58) | CA1CA2SMN1; SMN2HTTNPC1 | |
| SCHEMBL24413361 | 0.87 | CA1 (0.65) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL8628814 | 0.86 | CASR (0.55) | CA1CA2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4837793 | 0.86 | CA1 (0.63) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL5277825 | 0.85 | CA1 (0.62) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL31203371 | 0.84 | CA1 (0.64) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL16747675 | 0.83 | GAA (0.61) | CA1CA2SMN1; SMN2HTTNPC1 | |
| SCHEMBL31203477 | 0.83 | CA1 (0.62) | CA1CA2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |