Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | THRB | P10828 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909435 | 1.00 | MAPT (0.56) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL8908836 | 1.00 | MAPT (0.56) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL8909553 | 1.00 | MAPT (0.56) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL8908000 | 1.00 | MAPT (0.56) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL8907744 | 1.00 | MAPT (0.56) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL9868231 | 0.99 | MAPT (0.56) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL9868422 | 0.96 | MAPT (0.57) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL9802107 | 0.96 | MAPT (0.59) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL9868959 | 0.91 | KDM4E (0.47) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 | |
| SCHEMBL8907585 | 0.91 | KDM4E (0.47) | MAPTTHRBKDM4ESMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017698-A | Spirooxazine photochromic compounds | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0350009-A1 | Photochromic compound and photochromic composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-10 | — | — | EP | disclosed |