Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TOP2A | P11388 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811381 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9865282 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9865914 | 0.83 | TOP2A (0.55) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL9748481 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9670968 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9866107 | 0.81 | DPP4 (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9145514 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9147664 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9145492 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10817829 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992546-A | Process for preparing 6,8-diazabicyclo[3.2.2]nonane derivatives | WARNER-LAMBERT COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4968799-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4962108-A | A QUIN-4-ONE HAVING THE FOLLOWING RING SUBSTITUENTS; 1-ALKYL OR PHENYL, 3-CARBOXY DERIVATIVE, 6-FLUORO AND 8-BRIDGED N-HETEROCYCLIC RING | WARNER-LAMBERT COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4923879-A | CARBOXYLIC ACID DERIVATIVES WITH BRIDGED SIDECHAINS | WARNER-LAMBERT COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0305744-A2 | Quinoline, naphthyridine and benzoxazine-carboxylic acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |