Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407793 | 0.75 | — | — | |
| SCHEMBL17350222 | 0.74 | NPC1 (0.33) | NPC1PKMRAB9AMEN1KMT2A | |
| SCHEMBL9500903 | 0.74 | KDM4E (0.39) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11571870 | 0.74 | NPC1 (0.38) | NPC1PKMRAB9AMEN1KMT2A | |
| Urea SCHEMBL11571730 | 0.73 | NPC1 (0.35) | NPC1PKMRAB9AMEN1KMT2A | |
| SCHEMBL5549500 | 0.72 | — | — | |
| SCHEMBL2342947 | 0.72 | — | — | |
| SCHEMBL11657426 | 0.70 | — | — | |
| SCHEMBL6978891 | 0.68 | NPC1 (0.38) | NPC1PKMRAB9AMEN1KMT2A | |
| SCHEMBL9868678 | 0.67 | EPHX1 (0.40) | PKMMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051517-A | Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |