Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560875 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL698791 | 0.82 | — | — | |
| SCHEMBL6910529 | 0.81 | TSHR (0.36) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 | |
| Ethane SCHEMBL20838520 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL19056966 | 0.77 | GRIK1 (0.38) | ALDH1A1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5009666 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL2914469 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL385363 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL22144904 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL2990977 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1ALDH1A1KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015473-A | Beta-lactamase inhibitors | PFIZER INC. (US) | 1991-05-14 | — | — | US | disclosed |